How They Interact
High zinc intake induces metallothionein → binds copper in enterocytes → prevents absorption → copper deficiency. Risk: >40mg/day zinc for months.
Optimal Ratio
8-15:1 Zn:Cu
Practical Recommendation
Supplement 1-2mg copper per 25-30mg zinc if supplementing long-term. Food sources of copper: liver, oysters, dark chocolate, sunflower seeds.
⏱️ Timing
Take zinc and copper at different times of day for best absorption of each.