Quick Verdict
Creatine Monohydrate
Most researched sports supplement. Increases phosphocreatine stores for ATP regeneration during high-intensity exercise.
Evidence: strong (1000+ studies)
Caffeine
Most consumed psychoactive. Adenosine antagonist. Well-established ergogenic aid across nearly all exercise modalities.
Evidence: strong (1300+ studies)
Side-by-Side Comparison
| Creatine Monohydrate | Caffeine | |
|---|---|---|
| Category | performance | performance |
| Evidence Level | strong | strong |
| Studies | 1000+ | 1300+ |
| Dosage | 3-5 g | 3-6 mg/kg |
Stack Compatibility
Creatine Monohydrate: Beta-alanine, Caffeine, HMB, Whey Protein
Caffeine: L-theanine (1:2 ratio caffeine:theanine), Creatine, Tyrosine
Which Should You Choose?
Both serve different purposes. Choose based on your priority.