How It Works
Provides specific amino acids (glycine, proline, hydroxyproline) that are rate-limiting for collagen synthesis. Stimulates fibroblasts to produce new collagen. May work via glycine's anti-inflammatory and sleep-promoting effects.
Dosage & Timing
Optimal Timing
Take with food. Consistency matters more than timing for most supplements.
Cycling & Duration
No cycling required — safe for continuous daily use.
Best Forms (Ranked)
Best for skin, hair, nails. Most researched. Our top pick.
From fish. Better absorption claimed. More expensive.
For joint health specifically. Much lower dose (40mg). Different mechanism.
Evidence-Based Benefits
- Skin elasticity and hydration improvement (8-12 weeks)
- Joint pain reduction (moderate evidence)
- Nail strength and growth
- Gut lining support (glycine)
- Sleep quality (via glycine content)
Side Effects & Safety
- Digestive discomfort at high doses
- Fishy aftertaste (marine collagen)
- Not a complete protein — don't count toward daily protein target
✅ Good For
- Skin aging prevention
- Joint pain (especially athletes)
- Gut health support
- Those eating mostly muscle meat (low glycine intake)
- Nail/hair strength
⚠️ Skip If
- Vegetarians/vegans
- Those getting enough glycine from bone broth/whole-animal eating
- Kidney disease (high protein load)
Stacks Well With
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